Introduction of collagen manufacturers

1. Due to work fatigue and lack of sleep, the skin is dull and dull, yellowed, and skin elasticity is poor, and other adverse symptoms of skin aging.
2. Skin aging phenomena such as skin sagging, sagging, wrinkles and dryness caused by age and solar radiation.
3. Due to the strong secretion of abnormal melanin in the body and a large amount of deposits on the surface of the skin, the skin cannot metabolize abnormal melanin in time, forming various stains.
4. Due to long-term outdoor activities and improper skin maintenance, the skin is damaged, fine lines appear prematurely, dry skin, peeling, redness, and enlarged pores.
5. Due to the endocrine dysfunction, poor skin texture, oily and dark skin, color marks and pigmentation left by acne.
6, due to irregular life, smoking and other factors, caused by dark circles, bags under the eyes and other problems.
7. Long-term work beside the computer, computer radiation causes hair loss and endocrine disorders.
8. The skin is prone to allergies, dense blackheads, and large areas of skin death due to the selection of inferior cosmetics or hormones.

Collagen is the main component of human tissues. It has an inseparable relationship with various organs and cells of the human body, so it is used in the repair and regeneration of human organs and tissues. Related medical applications of collagen include collagen sponge, silk glands, membranes (surgical hemostasis, used for cardiovascular, nerve, oral, orthopedics, skin, obstetrics and gynecology operations, etc.) wound dressings, artificial skin, blood vessels, heart valves, cornea Protective materials, injectable collagen (used for wrinkle removal, soft tissue plump filling, treatment of urinary incontinence, urine reflux, orthopedic tissue regeneration filler), drug-assisted mechanism, collagen matrix template and other uses. Generally speaking, the basic unit of protein is amino acid, and its collagen is one of the main components to maintain firmness and elasticity.

In terms of types, there are more than 20 types of collagen in the human body. Different types of collagen differ in their molecular structure and immunological characteristics. They can be classified into three types according to tissues:
The first type: Type I-III interstitial collagen, which is mainly found in tissues such as skin and tendons. It is the collagen between cells and has strong tensile properties. Among them, type II collagen is produced by malignant bone cells.
The second type: basement membrane collagen has type IV-Ⅶ glue glands as basement membrane collagen, which mainly exists in the organs.
The third category: Cartilage collagen has types IX-XI, which are related to the formation of cartilage with trace collagen in cartilage.
From the structural point of view, the molecular structure of collagen is unique. In the electron microscope, it can be seen that the three molecules present a helical structure and have multiple types. The amino acid composition of the collagen peptide chain is unique. The content of glycine is one third, proline and hydroxyproline. Amino acids account for 10% each. Hydroxyproline is only found in collagen in animal tissues. The collagen conversion rate in skin is generally slow. Children’s skin is mainly type III, and adult skin is mainly type I. As we age, cross-linked tendons increase, and collagen fibers become tighter, which is related to skin aging and stiffness, so the skin appears to be loose.
From the perspective of the biological function of collagen, collagen has the highest content in the extracellular matrix (skin), and has the highest rigidity and tensile strength. It is the skeletal structure in the extracellular matrix. In addition, other components in the extracellular matrix can be combined with collagen. Combination constitutes a unity of structure and function. At the same time, various types of collagen have a certain selectivity when combined with extracellular matrix components.